11263-1-AP-产品快照
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- 11263-1-AP
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- 11263-1-AP
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产品介绍
11263-1-AP
Proteintech - 11263-1-AP - Rabbit Polyclonal Anti-OCT4 Antibody, Proteintech Group (Each (150µl))
11263-1-AP
Expression of the Oct-4 transcription factor is associated with an undifferentiated phenotype of human and mouse embryonic stem cells and germ cells. Oct-4 (Octamer-4) is a homeodomain transcription factor of the POU family (POU5F1) involved in regulation of pluripotency during normal development and is detectable in embryonic stem (ES) and germ cells. Its expression is associated with an undifferentiated phenotype and tumors. In fact, gene knockdown of Oct4 promotes differentiation, thereby demonstrating a role for this factor in human ES cell self-renewal. As such, it is frequently used as a marker for undifferentiated ES cells or iPS (induced pluripotent stem) cells. Oct4 is one of the four key transcription factors (Oct4, Sox2, c-Myc, and KLF4) used to reprogram mouse and human fibroblasts to a pluripotent state as well as generate patient-specific iPS cells. Affinity purified rabbit anti-Oct4 can be used to demonstrate pluripotency of ES and iPS cells. This listing is for Each (150µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Size 150 µL Application WB:Mouse Brain Tissue, 1:500-1:5000; IHC:Human Colon cancer Tissue, 1:20-1:200; IF:Human embronic stem Cells, 1:20-1:200 Tested Applications ELISA, IHC, IF, WB Unit Each (150µl) Antibody Isotype IgG Antibody Type Primary Antigen 4-Oct ChIP No Clonality Polyclonal ELISA Yes Flow Cytometry No Gel Shift No Host Rabbit ImmunoChemistry Yes ImmunoFluorescence Yes ImmunoPrecipitation No Immunogen Recombinant Protein Neutralisation No Purification Antigen affinity Purification Reactivity Human, Mouse, Rat Shipping Temperature Store at -20C Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Western Blot Yes
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