25-375-产品快照
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产品介绍
25-375
ProSci - 25-375 - MCM8 Antibody, ProSci (Each (50µG))
25-375
This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. MCM8 antibody can be used for detection of MCM8 by ELISA at 1:62500. MCM8 antibody can be used for detection of MCM8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. Antibody is purified by peptide affinity chromatography method. Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. This listing is for Each (50µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science > R&d > Chemicals Size 50 µg Host Rabbit Species Reactivity Human, Mouse, Rat Tested Applications E, WB Unit Each (50µG) Immunogen A synthetic peptide corresponding a region of human MCM8. Monoclonal/Polyclonal Polyclonal Physical Form Lyophilized Tested Applications E, WB
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