32-211-产品快照
- 品牌:
- 32-211
- 型号:
- 32-211
* 所有产品信息均源于第三方公开数据或用户上传,工业链仅整合供参考,真实价格货期请联系供应商确认.
供应商名称 | 电话 | 备注 |
---|---|---|
暂无展示,可咨询在线客服 | 400-811-6961 | 微信咨询,as10@gchane.com , QQ3350168184 |
产品介绍
32-211
ProSci - 32-211 - RET Antibody [6E4C4], ProSci (Each (100µl))
32-211
RET (ret proto-oncogene) is a member of the cadherin superfamily and a receptor tyrosine kinase, which are cell-surface molecules that transduce signals for cell growth and differentiation. It can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin and artemin. Alterations in the corresponding Ret gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma and a congenital developmental disorder known as Hirschsprung抯 disease. The Tyr905 residue located in the Ret kinase domain plays a crucial role in Ret catalytic and biological activity. Substitution of Phe for Tyr905 dramatically inhibits Ret autophosphorylation activity. Western Blot:1:500 - 1:2, 000 IHC(P):1:500 - 1:2, 000 ELISA:Propose dilution 1:10, 000. Determining optimal working dilutions by titration test. Ascitic fluid containing 0.03% sodium azide. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. This listing is for Each (100µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Size 0.1mL Host Mouse Clone 6E4C4 Species Reactivity Human Tested Applications E, WB Unit Each (100µl) Immunogen Purified truncated recombinant RET (aa896-1063)-GST fusion protein is expressed in E. Coli strain BL21 (DE3). Monoclonal/Polyclonal Monoclonal Tested Applications E, WB