GTX116018-产品快照
- 品牌:
- GTX116018
- 型号:
- GTX116018
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|---|---|---|
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 微信咨询，cs11@gchane.com , QQ1429311537
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产品介绍
GTX116018
Genetex - GTX116018 - CD45 antibody (Each (100µl))
GTX116018
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq] This listing is for Each (100µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science > R&d > Chemicals Antigen CD45 Host Rabbit Reactivity Human, Mouse Isotype IgG Molecular Weight 147 kDa Unit Each (100µl) Application Note Suggested starting dilutions are as follows: WB: 1:500-1:3000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry No Immunofluorescence Yes Immunogen Synthetic peptide contain a sequence corresponding to a region within amino acids 914 and 964 (P08575) of CD45 Immunoprecipitation No Monoclonal/Polyclonal Polyclonal Neutralization No Purification Purified by antigen-affinity chromatography. Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Storage Instruction Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Tested Applications ICC/IF, WB Type Primary Western Blot Yes
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