48-592-产品快照
- 品牌:
- 48-592
- 型号:
- 48-592
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产品介绍
48-592
ProSci - 48-592 - TGFBR1 Antibody, ProSci (Each (50µG))
48-592
TGFBR1, an Activin/TGFb type protein kinase, is a member of the transforming growth factor-beta (TGFb) signal transduction pathway which controls multiple intracellular functions and the development and homeostasis of most organs and tissues. TGFBR1 is recruited into a heteromeric complex and is phosphorylated by ligand-bound transforming growth factor beta receptor type 2 (TGFBR2). Activated TGFBR1 phosphorylates the receptor-regulated signaling proteins Smad2 and Smad3 which translocate to the nucleus to activate transcription. Mutations in, or loss of expression of, TGFBR1 have been identified in a large number of different tumors and in Loeys-Dietz syndrome. TGFBR1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200. PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide. Store TGFBR1 antibody at 2-8 °C for up to 1 year. Avoid repeated freeze-thaw cycles. This listing is for Each (50µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Size 0.05 mg Host Rabbit Species Reactivity Human, Mouse, Rat Tested Applications WB, IHC Unit Each (50µG) Immunogen TGFBR1 antibody was raised against amino acids 158 - 179 of TGFBR1 (Human). Monoclonal/Polyclonal Polyclonal Physical Form Liquid Tested Applications WB, IHC
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