48-604-产品快照
- 品牌:
- 48-604
- 型号:
- 48-604
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产品介绍
48-604
ProSci - 48-604 - CBX4 Antibody, ProSci (Each (50µG))
48-604
PC2 is the human homolog of the Drosophila 'Polycomb' (Pc) protein which has been identified as a gene family member associated with a cellular memory system that is responsible for the inheritance of gene activity by progeny cells. The human Pc homolog gene is more closely related to a Xenopus Pc homolog, XPc, than to a previously described human Pc homolog, CBX2 (hPc1). However, the hPc2 and CBX2/hPc1 proteins are shown to colocalize in interphase nuclei of human U-2 OS osteosarcoma cells, suggesting that the proteins are part of a common protein complex. The human protein is believed to function as a repressor of proto-oncogene activity and that interference with hPc2 function can lead to derepression of proto-oncogene transcription and subsequently to cellular transformation. Other reports describe PC2 as a protein that has SUMO E3 activity for the corepressors CtBP and CtBP2. CBX4 antibody can be used in Western Blot, and immunohistochemistry starting at 20 μg/mL. Immunoaffinity Chromatography 0.02 M potassium phosphate, 0.15 M NaCl, pH 7.2, 0.01% sodium azide. Aliquot and store at -20°C. Avoid multiple freeze-thaw cycles. This listing is for Each (50µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Size 0.05 mg Host Rabbit Species Reactivity Human Tested Applications E, WB, IHC, IF Unit Each (50µG) Immunogen CBX4 antibody was raised against amino acids 95 - 107 of CBX4 (Human). Monoclonal/Polyclonal Polyclonal Physical Form Liquid Tested Applications E, WB, IHC, IF
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