GTX22756

GTX22756-产品快照

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GTX22756
型号:
GTX22756

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产品介绍

GTX22756

Genetex - GTX22756 - Rabbit IgM antibody (FITC) (Each (500µl))

GTX22756

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as 'natural' blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences. Class specific anti immunoglobulin antibodies are useful for: The characterization of malignant B cell proliferations. All but acute lymphocytic leukemias share either surface or intra cytoplasmic Ig with an isotypic restriction, which suggest the monoclonal nature of the cell population. Most of the chronic lymphocytic leukemias, non Hodgkin lymphomas and Burkitt's lymphoma bear surface IgM, whereas plasmocytes from Waldenstres are less frequently found. On the other hand multiple myelomas are usually of the IgG or IgA type. Characterization of plasma cells in inflammatory conditions: Plasma cell typing can be of use for the classification of intestinal inflammatory conditions such as inflammatory bowel disease and allergic conditions. In the latter a specific increase in the number of IgE plasma cells can be demonstrated. This listing is for Each (500µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen Rabbit IGM Host Goat Reactivity Rabbit Isotype IgG Unit Each (500µl) Application Note Recommended Starting Dilutions: ICC/ ICC/IF: Use at a dilution of 1/200 - 1/2000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. ChIP ChIP - NO ELISA ELISA - NO Flow Cytometry Flow Cytometry - NO Gel Shift Gel Shift - NO ImmunoChemistry ImmunoChemistry - NO ImmunoFluorescence ImmunoFluorescense - YES ImmunoPrecipitation ImmunoPrecipitation - NO Monoclonal/Polyclonal Polyclonal Neutralisation Neutralisation - NO Purification Immunogen affinity purified Storage Buffer PBS pH 7.2, 0.2% BSA and 0.1% sodium azide Storage Instruction Keep as concentrated solution, aliquot and store at 4°C. Tested Applications ICC/IF Type Secondary Western Blot No

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