40-1276-U100-产品快照
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产品介绍
40-1276-U100
Tonbo Biosciences - 40-1276-U100 - In Vivo Ready Anti-Mouse Ly-6G (1A8) (Each (100µG))
40-1276-U100
The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is expressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immune responses. The DTA-1 antibody may be used for analysis of GITR expression on T cells, and is also commonly used in vitro as an agonistic antibody to induce GITR signaling in various assays. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science > Life Science > Cell Biology Size 100 μg Antigen Ly-6G Host Rat Reactivity Mouse Clone 1A8 Conjugate In Vivo Ready Isotype IgG2a, k Unit Each (100µG) Storage Conditions Store undiluted at 2-8°C, protect from light, do not freeze. Tested Applications Flow Cytometry
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