AG40A0014C010-产品快照
- 品牌:
- AG40A0014C010
- 型号:
- AG40A0014C010
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产品介绍
AG40A0014C010
AdipoGen - AG40A0014C010 - Angiopoietin-1 (human) (rec.) (Each (10µG))
AG40A0014C010
Angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. This listing is for Each (10µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Host CHO cells Form Liquid. Size 10 µg Unit Each (10µG) Biological Activity Induces phosphorylation of Tie-2 in primary cultured human vascular endothelial cells (HUVECs). The protein forms mainly tetrameric structures. Clonality Protein Concentration ~0.2mg/ml Long Term Storage -20°C Molecular Weight ~57kDa (SDS-PAGE) Purity >90% (SDS-PAGE) Sequence Human angiopoietin-1 (aa 20-498) is fused at the N-terminus to a FLAG -tag. Short Term Storage +4°C Species Crossreactivity Human Specificity Binds to human Tie-2. Stability Working aliquots are stable for up to 3 months when stored at -20°C. Storage Buffer 0.2µm-filtered solution in PBS containing 0.02% CHAPS.
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