AG20A0077C100-产品快照
- 品牌:
- AG20A0077C100
- 型号:
- AG20A0077C100
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产品介绍
AG20A0077C100
AdipoGen - AG20A0077C100 - anti-Progranulin (mouse), mAb (PG319-1) (Each (100µG))
AG20A0077C100
Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer's Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Isotype Rat IgG2a kappa Clone PG319-1 Form Liquid. Size 100 µg Unit Each (100µG) Applications ELISA , WB Clonality Monoclonal Antibody Concentration 1mg/ml Immunogen Recombinant mouse progranulin. Long Term Storage -20°C Short Term Storage +4°C Species Crossreactivity Mouse Specificity Recognizes mouse progranulin. Detects a band of ~90kDa by Western blot. Storage Buffer 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.