GTX10120-产品快照
- 品牌:
- GTX10120
- 型号:
- GTX10120
* 所有产品信息均源于第三方公开数据或用户上传,工业链仅整合供参考,真实价格货期请联系供应商确认.
供应商名称 | 电话 | 备注 |
---|---|---|
暂无展示,可咨询在线客服 | 400-811-6961 | 微信咨询,as10@gchane.com , QQ3350168184 |
产品介绍
GTX10120
Genetex - GTX10120 - MUC1 antibody [M4H2] (Each (100µG))
GTX10120
MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC-1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands.The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen MUC1 Host Mouse Reactivity Human Clone M4H2 Isotype IgG Unit Each (100µG) Application Note ELISA: Use at an assay dependent dilution. Can be used in ELISA pairs with GTX28322, 10117, 10123 and 10115. IF: Use at an assay dependent dilution. IHC: Use at an assay dependent dilution. Can be used for immunohistochemical staining of sections of breast, lung?and ovarian tumor tissues. Compatible with commonly used histological fixatives. IHC-P: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. ChIP No ELISA Yes Flow Cytometry No Gel Shift No Immunochemistry Yes Immunofluorescence Yes Immunogen High molecular weight (more than 300 kDa) glycoprotein from human milk-fat globule molecule. Immunoprecipitation No Monoclonal/Polyclonal Monoclonal Neutralization No Purification Protein A purified Storage Buffer Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide Storage Instruction Keep as concentrated solution, aliquot and store at 4°C. Tested Applications ELISA, ICC/IF, IHC-P, IHC-Fr Type Primary Western Blot No