PM-2348-产品快照
- 品牌:
- PM-2348
- 型号:
- PM-2348
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产品介绍
PM-2348
ProSci - PM-2348 - DC-SIGN Monoclonal Antibody, Prosci Inc (Each (100µG))
PM-2348
DC-SIGN Monoclonal Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR are known to exisit. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Size 0.1 mg Host Mouse Clone 8B6 Species Reactivity Human Unit Each (100µG) Immunogen A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN. Monoclonal/Polyclonal Monoclonal Purification Immunoaffinity chromotography purified IgG Storage Buffer PBS containing 0.02% sodium azide Tested Applications E, WB, IHC
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