GTX11425-产品快照
- 品牌:
- GTX11425
- 型号:
- GTX11425
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产品介绍
GTX11425
Genetex - GTX11425 - Syntrophin antibody [1351] (Each (50µG))
GTX11425
Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a, 1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus. This listing is for Each (50µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen Syntrophin Host Mouse Reactivity Amphibians, Chicken, Dog, Human, Mouse, Rat Clone 1351 Isotype IgG1 Unit Each (50µG) Application Note Recommended Starting Dilutions: For IF: Use at a concentration of 1 µg/ml. For IP: Use at an assay dependent dilution. For WB: Use at a concentration of .2 Mg/ml. Detects a band of approximately 58 kDa, representing syntrophin from rat and mouse cell extracts. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry No Immunofluorescence Yes Immunogen Whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane. Immunoprecipitation Yes Monoclonal/Polyclonal Monoclonal Neutralization No Purification Affinity Purified Storage Buffer PBS containing 1 mg/ml BSA and 0.05% sodium azide. Storage Instruction Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Tested Applications ICC/IF, IP, WB Type Primary Western Blot Yes
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