80-0042-U025-产品快照
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- 80-0042-U025
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- 80-0042-U025
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产品介绍
80-0042-U025
Tonbo Biosciences - 80-0042-U025 - redFluor 710 Anti-Mouse CD4 (RM4-5) (Each (25µG))
80-0042-U025
The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta2-domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The RM4-5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the RM4-5 antibody and an alternative antibody, Anti-Mouse CD4 clone GK1.5, will “compete” for binding, i.e. RM4-5 antibody is able to block GK1.5 antibody binding to cells. In contrast, RM4-5 antibody does not block the binding of Anti-Mouse CD4 clone RM4-4 to cells. This listing is for Each (25µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science > Life Science > Cell Biology Size 25 μg Antigen CD4 Host Rat Reactivity Mouse Clone RM4-5 Conjugate redFluor 710 Isotype IgG2a, k Unit Each (25µG) Storage Temperature Store Undiluted at 2 to 8°C; Protect from Light; Do Not Freeze. Synonyms L3T4, T4 Tested Applications Flow Cytometry
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