70-1243-U100-产品快照
- 品牌:
- 70-1243-U100
- 型号:
- 70-1243-U100
* 所有产品信息均源于第三方公开数据或用户上传,工业链仅整合供参考,真实价格货期请联系供应商确认.
供应商名称 | 电话 | 备注 |
---|---|---|
暂无展示,可咨询在线客服 | 400-811-6961 | 微信咨询,cs10@gchane.com , QQ1653501665 |
产品介绍
70-1243-U100
Tonbo Biosciences - 70-1243-U100 - Purified Anti-Mouse CD274 (PD-L1, B7-H1) (10F.9G2) (Each (100µG))
70-1243-U100
The 10F.9G2 antibody is specific for mouse CD274, more commonly known as PD-L1 or B7-H1, which acts as a ligand for the T cell co-regulatory receptor PD-1 (CD279). This interaction modulates T cell antigen receptor (TCR) signaling and therefore T cell activation. PD-L1 binding to PD-1 expressed on CD4- CD8- thymocytes participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-L1 may also bind PD-1 following the receptor's inducible expression on activated, mature T cells, where it has been proposed to limit T cell activation. PD-L1 is one of a group of “B7” ligands whose interactions with the CD28 receptor family, also including CTLA-4 (CD152), provide a balance of co-stimulatory /co-inhibitory signaling important in T cell activation, tolerance, and autoimmunity. The 10F.9G2 antibody may be used as a marker for PD-L1 expression on T and B cells, NK cells and on dendritic cells. It is also widely used for analysis of receptor-ligand interaction and function(s) in vitro and in vivo. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Installation Test & Maintenance > Test Equipment > Laboratory Supplies Size 100 μg Antigen CD274 Host Rat Reactivity Mouse Clone 10F.9G2 Conjugate Purified Isotype IgG2b, k Unit Each (100µG) Storage Temperature Store Undiluted at 2 to 8°C; Protect from Light; Do Not Freeze. Synonyms B7H1, PDL-1, PDL1 Tested Applications Flow Cytometry