GTX13730-产品快照
- 品牌:
- GTX13730
- 型号:
- GTX13730
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产品介绍
GTX13730
Genetex - GTX13730 - TLR7 antibody - 50µg (Each (50µG))
GTX13730
The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL 1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1 10) have been described. Stimulation of the NFkB signaling pathway by TLR7 suggests that it plays a role in immune response. This listing is for Each (50µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen TLR7 Host Rabbit Reactivity Human, Mouse, Rat Isotype IgG Unit Each (50µG) Application Note FACS: Use at a concentration of 2 - 5 μg/1 x 10^6cells (Ramos or Raw cells). WB: Use at a concentration of 1 - 3 μg/ml for raw cell lysate. Predicted molecular weight: 121 kDa. In human Ramos cells, additional bands are seen. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. ChIP No ELISA No Flow Cytometry Yes Gel Shift No Immunochemistry Yes Immunofluorescence No Immunogen Synthetic peptide: LSHNQLTTVPERLSNCSRSLKNL conjugated to KLH, corresponding to amino acids 706-728 of Human TLR7. Immunoprecipitation No Monoclonal/Polyclonal Polyclonal Neutralization No Purification Protein G purified Storage Buffer Preservative: 0.05% Sodium Azide, 0.2% GelatinConstituents: PBS Storage Instruction Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. Tested Applications FACS, IHC-Fr, WB Type Primary Western Blot Yes
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