20249-1-AP-产品快照
- 品牌:
- 20249-1-AP
- 型号:
- 20249-1-AP
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产品介绍
20249-1-AP
Proteintech - 20249-1-AP - Rabbit Polyclonal Anti-CPLX2 Antibody, Proteintech Group (Each (150µl))
20249-1-AP
Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Neuronal specific complexin 1 (CPLX1) has inhibitory and stimulatory effects on exocytosis by clamping trans-SNARE complexes in a prefusion state and promoting conformational changes to facilitate membrane fusion following cell stimulation. Complexin2 (CPLX2) is a pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals, it is downregulated in schizophrenic patients suffering from depression, animal models of depression and neurological disorders such as Huntington's disease in which depression is a major symptom. This antibody is expected to specifically recogize CPLX2 but not other complexins. This listing is for Each (150µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Size 150 µL Application WB:Mouse Brain Tissue, 1:500-1:5000; IHC:Human Brain Tissue, 1:20-1:200 Tested Applications ELISA, WB, IHC Unit Each (150µl) Antibody Isotype IgG Antibody Type Primary Antigen CPLX2 ChIP No Clonality Polyclonal ELISA Yes Flow Cytometry No Gel Shift No Host Rabbit ImmunoChemistry Yes ImmunoFluorescence No ImmunoPrecipitation No Immunogen Peptide Neutralisation No Purification Antigen affinity Purification Reactivity Human, Mouse, Rat Shipping Temperature Store at -20C Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Western Blot Yes