18834-1-AP-产品快照
- 品牌:
- 18834-1-AP
- 型号:
- 18834-1-AP
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产品介绍
18834-1-AP
Proteintech - 18834-1-AP - Rabbit Polyclonal Anti-ARHGAP24 Antibody, Proteintech Group (Each (150µl))
18834-1-AP
ARHGAP24, also named as FILGAP, is involved in cell polarity, cell morphology and cytoskeletal organization. ARHGAP24 acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. ARHGAP24 controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. ARHGAP24 can suppress the activity of RAC1 and CDC42 in vitro. Its overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis. The antibody may recognize all the isoforms of ARHGAP24 except isoform 5. This listing is for Each (150µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Size 150 µL Application WB:Mouse ovary Tissue, 1:500-1:5000; IHC:Human Kidney Tissue, 1:20-1:200 Tested Applications ELISA, WB, IHC Unit Each (150µl) Antibody Isotype IgG Antibody Type Primary Antigen ARHGAP24 ChIP No Clonality Polyclonal ELISA Yes Flow Cytometry No Gel Shift No Host Rabbit ImmunoChemistry Yes ImmunoFluorescence No ImmunoPrecipitation No Immunogen Peptide Neutralisation No Purification Antigen affinity Purification Reactivity Human, Mouse, Rat, Dog, Zebrafish Shipping Temperature Store at -20C Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Western Blot Yes
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