HF220SCFC050

HF220SCFC050-产品快照

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HF220SCFC050
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HF220SCFC050

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产品介绍

HF220SCFC050

AdipoGen - HF220SCFC050 - SCF (human):Fc (human) (rec.) (non-lytic) (Each (50µG))

HF220SCFC050

The extracellular domain of human SCF (aa 26-187) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels. This listing is for Each (50µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Host CHO cells Form Lyophilized from 0.2µm-filtered solution in PBS. Size 50 µg Unit Each (50µG) Biological Activity Shows the biological function of the SCF moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Clonality Protein Long Term Storage -20°C Purity >98% (SDS-PAGE) Short Term Storage +4°C Species Crossreactivity Human Stability Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

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