GTX28399-产品快照
- 品牌:
- GTX28399
- 型号:
- GTX28399
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产品介绍
GTX28399
Genetex - GTX28399 - BNIP3L antibody - 100µg (Each (100µG))
GTX28399
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designatedBnip3L, Bnip3a, and Nix (for Nip3-like protein X) (Matsushima, M. et al.; Yasuda, M. et al.; Chen, G, et al.). Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis (Yasuda, M. et al.; Chen, G, et al.). Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3Lis localized in mitochondria. The messenger RNA ofBnip3L is ubiquitously expressed in human tissues (Matsushima, M. et al.; Yasuda, M. et al.). Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen BNIP3L Host Rabbit Reactivity Human, Mouse Isotype IgG Unit Each (100µG) Application Note Western blot at 0.5 to 1 μg/ml. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry No Immunofluorescence No Immunogen peptide (DAQHESGQSSSRGSSH)corresponding to amino acids 77 to 92 of human origin, which are identical to those of mouse Bnip3L (3). Immunoprecipitation No Monoclonal/Polyclonal Polyclonal Neutralization No Purification IgG fraction Storage Buffer PBS with 0.02% sodium azide Storage Instruction Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. Tested Applications WB Type Primary Western Blot Yes
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