GTX101025-产品快照
- 品牌:
- GTX101025
- 型号:
- GTX101025
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产品介绍
GTX101025
Genetex - GTX101025 - PTEN antibody - 100µl (Each (100µl))
GTX101025
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. [provided by RefSeq] This listing is for Each (100µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen PTEN Host Rabbit Reactivity Human, Mouse Isotype IgG Molecular Weight 47 kDa Unit Each (100µl) Application Note Suggested starting dilutions are as follows: WB: 1:500-1:3000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry Yes Immunofluorescence Yes Immunogen Recombinant protein fragment contain a sequence corresponding to a region within amino acids 182 and 376 of PTEN Immunoprecipitation No Monoclonal/Polyclonal Polyclonal Neutralization No Purification Purified by antigen-affinity chromatography. Storage Buffer 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Storage Instruction Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Tested Applications ICC/IF, WB Type Primary Western Blot Yes
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