GTX100062-产品快照
- 品牌:
- GTX100062
- 型号:
- GTX100062
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产品介绍
GTX100062
Genetex - GTX100062 - ATF1 antibody (Each (100µl))
GTX100062
This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq] This listing is for Each (100µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen ATF1 Host Rabbit Reactivity Human Isotype IgG Molecular Weight 29 kDa Unit Each (100µl) Application Note Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. ChIP ChIP - NO ELISA ELISA - NO Flow Cytometry Flow Cytometry - NO Gel Shift Gel Shift - NO ImmunoChemistry ImmunoChemistry - NO ImmunoFluorescence ImmunoFluorescense - NO ImmunoPrecipitation ImmunoPrecipitation - NO Immunogen Synthetic peptide contain a sequence corresponding to a region within amino acids 208 and 260 (P18846) of ATF1 Monoclonal/Polyclonal Polyclonal Neutralisation Neutralisation - NO Purification Purified by antigen-affinity chromatography. Storage Buffer 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Storage Instruction Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Tested Applications WB Type Primary Western Blot Yes
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