GTX15471

GTX15471-产品快照

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GTX15471
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GTX15471

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产品介绍

GTX15471

Genetex - GTX15471 - MDM2 antibody - 1ml (Each (1ml))

GTX15471

Human homolog of murine double minute-2 (MDM2) and p53 function in mutual regulation: activation of p53 results in expression of MDM2 which consequently inhibits the ability of wild type p53 to stimulate expression of target genes. MDM2 is frequently overexpressed in the nuclei of soft tissue sarcomas, and to a much lesser extent in a wide variety of malignancies of bladder, breast, testes, cervix, glial cells. This listing is for Each (1ml) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen MDM2 Host Rabbit Reactivity Human, Mouse, Rat Isotype IgG Unit Each (1ml) Application Note For IHC-P: Use at a dilution of 1:50 for 10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0 for 10 minuttes followed by cooling at RT for 20 min. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry Yes Immunofluorescence No Immunogen Synthetic peptide corresponding to amino acids 154-167 of human MDM2. Immunoprecipitation No Monoclonal/Polyclonal Polyclonal Neutralization No Purification Immunogen affinity purified Storage Buffer Phosphate-buffered saline, pH 7.4, containing sodium azide and BSA Storage Instruction Keep as concentrated solution, aliquot and store at 4°C. Tested Applications IHC-P Type Primary Western Blot No

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