GTX13666-产品快照
- 品牌:
- GTX13666
- 型号:
- GTX13666
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产品介绍
GTX13666
Genetex - GTX13666 - NKIRAS1 antibody [184C278] (Each (100µG))
GTX13666
NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. Synthesis of IkBa is autoregulated. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g. External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first genes induced following NF-kB activation is IkBa. Recently, two proteins, kB-Ras1 and kB-Ras2 have been identified. These two proteins interact with PEST domains of IkBa and IkBb and decrease their rate of degradation. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen NKIRAS1 Host Mouse Reactivity Human, Mouse, Rat Clone 184C278 Isotype IgG1 Unit Each (100µG) Application Note WB: Use at a concentration of 0.5 - 1 μg/ml. Predicted molecular weight: 23 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry No Immunofluorescence No Immunogen Synthetic peptide: RVELLKKEIDKFKDKKEV, corresponding to amino acids 96-113 of Human NKIRAS1. Immunoprecipitation No Monoclonal/Polyclonal Monoclonal Neutralization No Purification Protein G purified Storage Buffer Preservative: 0.02% Sodium Azide; Constituents: PBS Storage Instruction Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. Tested Applications WB Type Primary Western Blot Yes
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