GTX61406-产品快照
- 品牌:
- GTX61406
- 型号:
- GTX61406
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产品介绍
GTX61406
Genetex - GTX61406 - AFP antibody [EP1017Y], C-term (Each (100µl))
GTX61406
Alpha-fetoprotein (AFP) is a serum glycoprotein protein produced in the liver or yolk sac of fetal staged mammals. AFP synthesis is minimal after birth and trace amount is expressed in the adult liver . AFP gene expression is regulated by the interactions between steroid hormone receptors and transcriptional factors in separate signal transduction pathways . AFP functions as a binding and transporting ligand and cell growth regulator. Elevated expression level of AFP has been implicated in colorectal, ovarian, pancreatic, testicular, and certain liver cancers. High levels of AFP is also seen in some diseases such as hepatitis and colitis. AFP is used as a screening marker for fetal abnormalities in pregnant women such as Down syndrome. Recently, AFP has been introduced as an anti-cancer drugs-ligand carrier, transporting drugs to target tumor cells, increasing anti-tumor efficiency . This listing is for Each (100µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen AFP Host Rabbit Reactivity Human Clone EP1017Y Isotype IgG Molecular Weight 70 kDa Unit Each (100µl) Application Note Recommended Starting Dilutions: For WB: Use at a dilution of 1:1, 000 - 2, 000 For IHC: Use at a dilution of 1:250-500 For IP: Use at a dilution of 1:50 Optimal working dilution for a specific application should be determined by the investigator. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry Yes Immunofluorescence No Immunogen A synthetic peptide corresponding to residues near the C-term of human AFP was used as an immunogen. Immunoprecipitation Yes Monoclonal/Polyclonal Monoclonal Neutralization No Purification Cell Supernatant Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Storage Instruction Store at -20 °C. Stable for 12 months from date of receipt. Tested Applications IHC-P, IP, WB Type Primary Western Blot Yes
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