GTX25247-产品快照
- 品牌:
- GTX25247
- 型号:
- GTX25247
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产品介绍
GTX25247
Genetex - GTX25247 - PAK1 + PAK2 + PAK3 (phospho Ser141) antibody (Each (50µl))
GTX25247
P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, members of which are activated by small molecular weight GTPases. The three most common isoforms are PAK 1, PAK 2, and PAK 3 (also known as alpha PAK, gamma PAK, and beta PAK, respectively). These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, interaction with Src homology 3 (SH3) domains, and caspase mediated proteolytic cleavage. Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), catalyzed by Cdc42, is required for activation of PAK. This listing is for Each (50µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen PAK1 + PAK2 + PAK3 (Phospho SER141) Host Rabbit Reactivity Human, Rabbit, Rat Isotype IgG Unit Each (50µl) Application Note WB: Use at a concentration of 0.1 - 1.0 μg/ml. Predicted molecular weight: 65 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry No Immunofluorescence No Immunogen Chemically synthesized phosphopeptide derived from a region of human PAK2 that contains serine 141. The sequence is conserved in rat and rabbit. Immunoprecipitation No Monoclonal/Polyclonal Polyclonal Neutralization No Purification Immunogen affinity purified Storage Buffer Preservative: 0.05% Sodium Azide; Constituents: PBS, 50% glycerol, 1mg/ml BSA (IgG, protease free). pH 7.3 Storage Instruction Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Tested Applications WB Type Primary Western Blot Yes
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