GTX100546

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GTX100546
型号:
GTX100546

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产品介绍

GTX100546

Genetex - GTX100546 - RhoC antibody (Each (100µl))

GTX100546

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq] This listing is for Each (100µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen RHOC Host Rabbit Reactivity Human, Mouse Isotype IgG Molecular Weight 22 kDa Unit Each (100µl) Application Note Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry Yes Immunofluorescence Yes Immunogen Recombinant fragment corresponding to a region within amino acids 11 and 193 of RhoC (Uniprot ID#P08134) Immunoprecipitation No Monoclonal/Polyclonal Polyclonal Neutralization No Purification Purified by antigen-affinity chromatography. Storage Buffer 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Storage Instruction Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Tested Applications IHC-P, WB Type Primary Western Blot Yes

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