GTX62211-产品快照
- 品牌:
- GTX62211
- 型号:
- GTX62211
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产品介绍
GTX62211
Genetex - GTX62211 - TNFAIP3 antibody [EPR2663] (Each (100µl))
GTX62211
Tumor necrosis factor, alpha-induced protein 3 (TNFAIP3) is a de-ubiquitinating enzyme that contains an N-terminal catalytic domain belonging to the ovarian-tumour superfamily of cysteine proteases . TNFAIP3 suppresses apoptosis. It is expressed in various cell types in response to a variety of stimuli that activate the transcription factor NF-kB, including Il-1, CD40 ligand, and PMA . TNFAIP3 has been strongly suggested as a key protein involved in tamoxifen resistance, and thus represents both a new breast cancer marker and a promising target for developing new strategies to prevent the emergence of acquired mechanisms of drug resistance in breast cancer . This listing is for Each (100µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen TNFAIP3 Host Rabbit Reactivity Human Clone EPR2663 Isotype IgG Molecular Weight 80 kDa Unit Each (100µl) Application Note Recommended Starting Dilutions: For WB: Use at a dilution of 1:1, 000 - 10, 000 For IHC: Use at a dilution of 1:50 - 100 For ICC: Use at a dilution of 1:100 For FACS: Use at a dilution of 1:50 Optimal working dilution for a specific application should be determined by the investigator. ChIP No ELISA No Flow Cytometry Yes Gel Shift No Immunochemistry Yes Immunofluorescence Yes Immunogen A synthetic peptide corresponding to residues in human TNFAIP3 was used as an immunogen. Immunoprecipitation No Monoclonal/Polyclonal Monoclonal Neutralization No Purification Cell Supernatant Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Storage Instruction Store at -20 °C. Stable for 12 months from date of receipt. Tested Applications FACS, ICC/IF, IHC-P, WB Type Primary Western Blot Yes