GTX61958-产品快照
- 品牌:
- GTX61958
- 型号:
- GTX61958
* 所有产品信息均源于第三方公开数据或用户上传，工业链仅整合供参考，真实价格货期请联系供应商确认.
| 供应商名称 | 电话 | 备注 |
|---|---|---|
| 暂无展示，可咨询在线客服 | 400-811-6961 |
 微信咨询，cs10@gchane.com , QQ1653501665
|
产品介绍
GTX61958
Genetex - GTX61958 - beta Catenin (phospho Thr41/pT45) antibody [EP1905Y] (Each (100µl))
GTX61958
Beta-catenin is a key regulatory protein involved in cell adhesion and signal transduction through the Wnt pathway, and plays important roles in development, cellular proliferation, and differentiation . Beta-catenin is phosphorylated at four serine and threonine residues at the N-terminus . Ser 45 is phosphorylated by CK1, and is thought to be a priming site for the phosphorylation by glycogen synthase kinase-3 (GSK-3) of the remaining three residues, Thr 41, Ser 37, and Ser 33 . Wnt signaling antagonizes the action of GSK-3, which in subsequent phosphorylation steps, leads to its degradation . Mutations in the Beta-catenin gene, CTNNB1, have been implicated in its accumulation and various forms of carcinomas . This listing is for Each (100µl) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen Catenin B (Phospho THR41/PT45) Host Rabbit Reactivity Human Clone EP1905Y Isotype IgG Molecular Weight 92 kDa Unit Each (100µl) Application Note Recommended Starting Dilutions: For WB: Use at a dilution of 1:10, 000 - 20, 000 For IP: Use at a dilution of 1:20 Optimal working dilution for a specific application should be determined by the investigator. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry No Immunofluorescence No Immunogen A phospho specific peptide corresponding to residues surrounding threonine 41 and 45 of human Beta-catenin was used as an immunogen. Immunoprecipitation Yes Monoclonal/Polyclonal Monoclonal Neutralization No Purification Cell Supernatant Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Storage Instruction Store at -20 °C. Stable for 12 months from date of receipt. Tested Applications IP, WB Type Primary Western Blot Yes
更多产品:
更多品牌:
