GTX23769-产品快照
- 品牌:
- GTX23769
- 型号:
- GTX23769
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产品介绍
GTX23769
Genetex - GTX23769 - PRMT1 antibody - Rabbit Polyclonal - ELISA, WB (Each (100µG))
GTX23769
Arginine methylation is an irreversible post translational modification that has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins (Histone-2A, 3, 4), IL enhancer binding factor, nuclear factors (NF-45, -90, ILF3, Nucleolin, STAT1, Poly(A)-binding protein II), cell cycle proteins (phosphoprotein phosphatase 2A), signal transduction proteins (FGF2, Fibrillarin, FN, INFAR1, Jak, MBP, Src-adaptor Sam68), apoptosis proteins (FADD, ICE-like protease), and viral proteins (Hepatitis C NS3 RNA Helicase, HIV TAR). The mammalian PRMT family currently consists of 5 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all five PRMT members have been developed. These antibodies can be utilized to explore arginine methylation and its regulatory functions. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen PRMT1 Host Rabbit Reactivity Human Isotype IgG Unit Each (100µG) Application Note ELISA: Use at a dilution of 1/1000. WB: Use at a dilution of 1/100 - 1/500. Predicted molecular weight: 40 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. ChIP ChIP - NO ELISA ELISA - YES Flow Cytometry Flow Cytometry - NO Gel Shift Gel Shift - NO ImmunoChemistry ImmunoChemistry - NO ImmunoFluorescence ImmunoFluorescense - NO Immunogen Synthetic peptide conjugated to KLH, corresponding a regio of amino acids 1-100 of Human PRMT 1. Immunoprecipitation No Monoclonal/Polyclonal Polyclonal Neutralization No Purification Protein G purified Storage Buffer PBS with 0.1% sodium azide Storage Instruction Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. Tested Applications ELISA, WB Type Primary Western Blot Yes
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