AG40B00743050-产品快照
- 品牌:
- AG40B00743050
- 型号:
- AG40B00743050
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产品介绍
AG40B00743050
AdipoGen - AG40B00743050 - TNF-R1 (human):Fc (human) (rec.) (Pack of 3 (50µµG))
AG40B00743050
TNF-R1 is a receptor for TNF-alpha and homotrimeric lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. This listing is for Pack of 3 (50µµG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Host HEK 293 cells Form Lyophilized. Size 3 x 50 µg Unit Pack of 3 (50µµG) Biological Activity TNF-R1:Fc fusion protein blocks TNF-alpha-mediated biological effect with an inhibitory activity in a concentration range of 0.1 to 1µg/ml. Clonality Protein Concentration 1mg/ml after reconstitution. Long Term Storage -20°C Molecular Weight ~60kDa (reducing SDS-PAGE) Purity >95% (SDS-PAGE) Sequence The extracellular domain of human TNF-R1 (aa 22-211) is fused to the Fc portion of human IgG1. Short Term Storage +4°C Species Crossreactivity Human , Mouse Specificity Binds human and mouse TNF-alpha. Stability Stable for at least 6 months after receipt when stored at -20°C. Storage Buffer Contains PBS.