28-527

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28-527
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28-527

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28-527

ProSci - 28-527 - GJB2 Antibody, ProSci (Each (100µG))

28-527

Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1; MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. GJB2 antibody can be used for detection of GJB2 by ELISA at 1:62500. GJB2 antibody can be used for detection of GJB2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. Antibody is purified by protein A chromatography method. Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science > R&d > Chemicals Size 100 µg Host Rabbit Species Reactivity Human, Dog Tested Applications E, WB Unit Each (100µG) Immunogen A synthetic peptide corresponding a region of human GJB2. Monoclonal/Polyclonal Polyclonal Physical Form Lyophilized Tested Applications E, WB

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