31-234-产品快照
- 品牌:
- 31-234
- 型号:
- 31-234
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产品介绍
31-234
ProSci - 31-234 - JUNB Antibody, ProSci (Each (100µG))
31-234
The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. JunB is involved in many types of human carcinoma including T-cell lymphomas, CML, primary cutaneous lymphomas. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.JunB is an important regulator of erythroid Differentiation. JUNB antibody can be used for detection of JUNB by ELISA at 1:62500. JUNB antibody can be used for detection of JUNB by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. Antibody is purified by protein A chromatography method. Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science > R&d > Chemicals Size 100 µg Host Rabbit Species Reactivity Human, Mouse, Rat, Dog Tested Applications E, WB Unit Each (100µG) Immunogen A synthetic peptide corresponding a region of human JUNB. Monoclonal/Polyclonal Polyclonal Physical Form Lyophilized Tested Applications E, WB