29-597-产品快照
- 品牌:
- 29-597
- 型号:
- 29-597
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产品介绍
29-597
ProSci - 29-597 - ADAMTS4 Antibody, ProSci (Each (50µG))
29-597
ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. ADAMTS4 antibody can be used for detection of ADAMTS4 by ELISA at 1:62500. ADAMTS4 antibody can be used for detection of ADAMTS4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. Antibody is purified by peptide affinity chromatography method. Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. This listing is for Each (50µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science > R&d > Chemicals Size 50 µg Host Rabbit Species Reactivity Human, Mouse, Rat Tested Applications E, WB, IHC Unit Each (50µG) Immunogen A synthetic peptide corresponding a region of human ADAMTS4. Monoclonal/Polyclonal Polyclonal Physical Form Lyophilized Tested Applications E, WB, IHC