GTX12995

GTX12995-产品快照

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GTX12995
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GTX12995

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产品介绍

GTX12995

Genetex - GTX12995 - Frizzled 7 antibody (N-Terminus) (Each (25µG))

GTX12995

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The Frizzled 7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Frizzled family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. Frizzled 7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. Frizzled 7 expression has been reported in brain, gastrointestinal tract, heart, fetal kidney, fetal lung, placenta, skeletal muscle, and various cancers. ESTs have been isolated from a wide variety of normal and cancer libraries. This listing is for Each (25µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Antigen FRIZZLED 7 Host Rabbit Reactivity Human Isotype IgG Unit Each (25µG) Application Note IHC-P: Use at a dilution of 1/100 - 1/200. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. ChIP ChIP - NO ELISA ELISA - NO Flow Cytometry Flow Cytometry - NO Gel Shift Gel Shift - NO ImmunoChemistry ImmunoChemistry - YES ImmunoFluorescence ImmunoFluorescense - NO Immunogen Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) Immunoprecipitation No Monoclonal/Polyclonal Polyclonal Neutralization No Purification Immunogen affinity purified Storage Buffer Preservative: 0.01% Sodium Azide; Constituents: PBS. pH 7.7 Storage Instruction Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. Tested Applications IHC-P Type Primary Western Blot No

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